Experts Debate Message Sent by Increased Cancer Survival Rates

Experts Debate Proton Therapy for Prostate Cancer

This was a prospective, phase 3, randomized trial of proton beam-based dose escalation in organ-confined prostate cancer. Just under 400 patients were randomly assigned to receive either 70.2 or 79.2 Gy. With a median follow-up of just under 9 years, there continues to be a substantial, statistically significant improvement in biochemical disease-free survival for those patients receiving the h...

Interpreting cancer survival rates.

Convergence Rates for Mixture-of-Experts

In mixtures-of-experts (ME) model, where a number of submodels (experts) are combined, there have been two longstanding problems: (i) how many experts should be chosen, given the size of the training data? (ii) given the total number of parameters, is it better to use a few very complex experts, or is it better to combine many simple experts? In this paper, we try to provide some insights to th...

Excessive Cytosolic DNA Fragments as a Potential Trigger of Graves’ Disease: An Encrypted Message Sent by Animal Models

Graves' hyperthyroidism is caused by autoantibodies directed against the thyroid-stimulating hormone receptor (TSHR) that mimic the action of TSH. The establishment of Graves' hyperthyroidism in experimental animals has proven to be an important approach to dissect the mechanisms of self-tolerance breakdown that lead to the production of thyroid-stimulating TSHR autoantibodies (TSAbs). "Shimojo...

Niosh Study of Firefighters Finds Increased Rates of Cancer

The study analyzed cancers and cancer deaths through 2009 among 29,993 firefighters from the Chicago, Philadelphia, and San Francisco fire departments who were employed since 1950. The study was led by NIOSH in collaboration with the National Cancer Institute and the Department of Public Health Sciences in the University of California at Davis. The study was supported in part by funding from th...